Markets / Top Edge

Top Edge Markets

Markets where our AI model diverges most from current crowd pricing. A positive edge means YES may be undervalued. A negative edge means NO may be undervalued.

Market Price

Current crowd consensus

AI Pulse Score

Our model's adjusted probability

Edge Score

Gap between the two — higher = more divergence

Positive edge = YES may be undervalued

Negative edge = NO may be undervalued

Not financial advice. For informational purposes only.

21 markets with edge score > 3 pts

Market	Market	AI	⚡ Edge	Conf	Verdict
Will Lantern Bioworks Lumina treatment be FDA Approved for preventing tooth deca… Manifold Science & Health	2.3%	5.8%	+3.5 pts	60	NO
Will there be an Opioid Vaccine available by the end of 2026? Manifold Science & Health	4.56%	8.06%	+3.5 pts	60	NO
Will NASA announce that there is life on K2-18b with a high degree probability b… Manifold Science & Health	1.97%	5.47%	+3.5 pts	60	NO
Will the highest temperature in Denver be between 82-83°F on March 24? Polymarket Science & Health	0.05%	35.5%	+3.5 pts	60	NO
Will Luigi Magione’s defense claim mental health or substance impairment in cour… Manifold Science & Health	49%	52.5%	+3.5 pts	55	~
[ACX 2026] Will the FDA approve a psilocybin treatment during 2026? Manifold Science & Health	13.94%	17.44%	+3.5 pts	55	NO
NASA confirms aliens before 2027? Manifold Science & Health	3.02%	8.5%	+3.5 pts	55	NO
Pythom Space achieves successful launch by end of Q1 2026? Manifold Science & Health	1%	4.5%	+3.5 pts	55	NO
Will climate change decimate humans before 2070? Manifold Science & Health	15.95%	19.45%	+3.5 pts	50	NO
Will a person get lost in space by 2035? Manifold Science & Health	17.61%	21.11%	+3.5 pts	50	NO
Will climate change decimate humans before 2090? Manifold Science & Health	19.11%	22.61%	+3.5 pts	50	NO
Will an adult movie be made in space and released by mid 2034? Manifold Science & Health	39.63%	43.13%	+3.5 pts	50	NO
Will we get a cure for cancer before 2033? Manifold Science & Health	18.76%	22.26%	+3.5 pts	50	NO
Will Michael Nielsen agree by 2030 that private-only funding for science signifi… Manifold Science & Health	12.14%	15.64%	+3.5 pts	50	NO
Will climate change decimate humans before 2050? Manifold Science & Health	9.61%	13.29%	+3.5 pts	50	NO
Will anyone be killed by falling space debris before the end of 2032? Manifold Science & Health	8.84%	12.34%	+3.5 pts	50	NO
Will NASA assign asteroid YR4 an impact probability of ≥4.0% before June 2029? Manifold Science & Health	2.48%	5.98%	+3.5 pts	50	NO
Will the FDA approved a drug that claims to reduce the number of hours of sleep … Manifold Science & Health	21.13%	21.44%	+3.5 pts	50	NO
Will the WHO declare an H5N1 pandemic before 2030? Manifold Science & Health	19.3%	24.42%	+3.5 pts	50	NO
Will there be 100 people in space at the same time before 2030? Manifold Science & Health	10.56%	14.06%	+3.5 pts	50	NO
Will FDA approve any mRNA vaccine against any type of herpes simplex infection b… Manifold Science & Health	24.94%	28.5%	+3.5 pts	50	NO